Topical Anesthetic Gel Dental topical anesthetics, like 20% Benzocaine gel and 5% Lidocaine cream, provide fast acting pain relief to patients during oral procedures. It is also used to provide relief for other kinds of patient discomfort including discomfort resulting from wearing orthodontic appliances. Most dental numbing cream takes effect approximately 15-30 seconds after application, making it a quick solution to pain a patient may be feeling. Additionally, anesthetics are available in either a spray or gel and come in a variety of flavors avoiding any kind of bad after taste. Scott's Dental Supply stocks a wide variety of topical anesthetics at every day low prices.